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26-08-2010
Direct renin inhibitor (DRI) is a new class of antihypertensive agent with the novel mechanism that directly inhibits the renin, which is the source of activation of the RAAS.
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29-10-2008
There are three major classes of CCBs (phenylalkylamines, dihydropyridines and benzothiazepines) with different characteristics and all are effective in lowering BP.
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23-07-2007
The use of diuretics is well established in the treatment of hypertension. Thiazide diuretics are cheap and are the most widely used antihypertensive agents.
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23-07-2007
Beta-blockers have long been established in the treatment of hypertension. They are particularly useful in hypertensive patients with effort angina, tachyarrhythmias or previous myocardial infarction where they have been shown to reduce cardiovascular morbidity and mortality.
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23-07-2007
ACEIs are effective in lowering BP. They are generally well tolerated and do not have adverse effects on lipid and glucose metabolism. Their safety profile is good. Their benefits have been demonstrated in certain groups of patients beyond BP reduction.
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23-07-2007
ARBs are specific angiotensin II receptor antagonists with many properties similar to those of ACEIs. Unlike ACEIs, persistent dry cough is not a problem.
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